肖游君

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主任医师 | 风湿免疫科

中山大学附属第一医院(三级甲等)

肖游君

 医生简介

医疗特长:本人专注于风湿免疫科常见病多发病如类风湿关节炎、系统性红斑狼疮、强直性脊柱炎、痛风、骨关节炎、干燥综合征等疾病的诊治

 

研究方向:

类风湿关节炎发病机制及诊治

主要教育和工作经历:

2003-2008年 南昌大学 本科

2008-2011年 中山大学附属第一医院 硕士

2011-2014年 中山大学附属第一医院 博士

 

社会兼职:

 

论著:

①        Zou Y(#),Xu S(#),Xiao Y(#),Qiu Q,Shi M,Wang J,Liang L,Zhan Z,Yang X,Olsen N,Zheng S G(*),Xu H(*). Long noncoding RNA LERFS negatively regulates rheumatoid synovial aggression and proliferation. J Clin Invest. 2018;128(10):4510-4524. (IF 12.282 )

②    Xiao Y(#),Liang L(#),Huang M(#),Qiu Q,Zeng S,Shi M,Zou Y,Ye Y,Yang X,Xu H(*). Bromodomain and extra-terminal domain bromodomain inhibition prevents synovial inflammation via blocking IkappaB kinase-dependent NF-kappaB activation in rheumatoid fibroblast-like synoviocytes. Rheumatology (Oxford). 2016;55(1):173-184.(IF 5.149

③        Wang J(#),Li R(#),Lin H(#),Qiu Q,Lao M,Zeng S,Wang C,Xu S,Zou Y,Shi M,Liang L,Xu H,Xiao Y(*). Accumulation of cytosolic dsDNA contributes to fibroblast-like synoviocytes-mediated rheumatoid arthritis synovial inflammation. Int Immunopharmacol. 2019;76:105791. (IF 3.361)

④        Xiao Y(#),Shi M(#),Qiu Q,Huang M,Zeng S,Zou Y,Zhan Z,Liang L,Yang X,Xu H(*). Piperlongumine Suppresses Dendritic Cell Maturation by Reducing Production of Reactive Oxygen Species and Has Therapeutic Potential for Rheumatoid Arthritis. J Immunol. 2016;196(12):4925-4934. (IF 4.718)

⑤    Xiao Y (#),Sun M (#),Zhan Z (#),Ye Y,Huang M,Zou Y,Liang L,Yang X,Xu H(*). Increased phosphorylation of ezrin is associated with the migration and invasion of fibroblast-like synoviocytes from patients with rheumatoid arthritis. Rheumatology (Oxford). 2014;53(7):1291-1300. (IF 5.149)

⑥        Xiao Y (#),Liang L(#),Pan Y,Lian F,Li L,Lin H,Fu D,Fan J,Yang X,Sun L,Xu H(*).Inhibitory effects of simvastatin on migration and invasion of rheumatoid fibroblast-like synoviocytes by preventing geranylgeranylation of RhoA. Rheumatol Int. 2013;33(2):389-399. (IF 2.2 )

 

专著:

 

其他主要工作成绩(比如获奖情况):

 执业点

中山大学附属第一医院(三级甲等)风湿免疫科