医疗特长：

    长期从事心血管发育与疾病的分子机制研究，主要从分子、细胞、小鼠模型以及病人多个层面研究蛋白质基因网络和非编码RNA基因网络如何协同调控心血管疾病的发生发展，并探索新的心血管疾病基因疗法。

研究方向：

    心血管疾病的基因调控网络

主要教育和工作经历：

    2018.12 至今，  国家卫健委辅助循环重点实验室，副主任

    2017.11 至今，  中山大学附属第一医院，研究员，博士生导师

    2010.11-2017.11，美国哈佛医学院波士顿儿童医院，讲师

    2009.8-2010.10， 美国哈佛医学院波士顿儿童医院，博士后

    2008.2-2009.7，  美国北卡莱罗纳州大学教皇山分校，博士后

    2002.9-2007.6，  中山大学，生物化学与分子生物学，博士

    1998.9-2002.6，  中山大学，生物化学，学士

社会兼职：

Frontiers in Cardiovascular Medicine杂志副主编

广东省医学会心血管分会基础研究学组副组长

论著：

【代表性论文】（#共同第一作者，*通讯作者）

Yan, Y.#, Tang, R. #, Li, B. #, Cheng, L.#, Ye, S., Yang, T., Han, Y.C., Liu, C., Dong, Y., Qu, L.H., Lui, K.O., Yang, J.H.* and Huang, Z.P.* The cardiac translational landscape reveals that micropeptides are new players involved in cardiomyocyte hypertrophy. Molecular Therapy. 2021, 29: 2253-2267. (IF: 12.91)

He, X.#, Liu, J.#, Gu, F., Chen, J., Lu, Y.W., Ding, J., Guo, H., Nie, M., Kataoka, M., Lin, Z., Hu, X., Chen, H., Liao, X., Dong, Y., Min, W., Deng, Z.L., Pu, W.T., Huang, Z.P.* and Wang, D.Z.* Cardiac CIP protein regulates dystrophic cardiomyopathy. Molecular Therapy. 2022, 30: 898-914. (IF: 12.91)

He, X.#, Du, T.#, Long, T.#, Liao, X.*, Dong, Y.*, Huang, Z.P.* Signaling cascades in the failing heart and emerging therapeutic strategies. Signal Transduction and Targeted Therapy. 2022, 7:134. (IF: 38.104)

Huang, Z.P.* and Wang, D.Z*. miR-22 in smooth muscle cells, a potential therapy for cardiovascular disease. Circulation. 2018, 137:1842-1845. (IF: 39.918)

Tang, R.#, Long, T.#, Lui, K.O., Chen, Y., and Huang, Z.P.* A Roadmap for Fixing the Heart: RNA Regulatory Networks in Cardiac Disease. Molecular Therapy - Nucleic Acids. 2020, 20:673-686. (IF: 10.183)

Huang, Z.P., Kataoka, M., Chen, J., Wu, G., Ding, J., Nie, M., Lin, Z., Liu, J., Hu, X., Ma, L., Zhou, B., Wakimoto, H., Zeng, C., Kyselovic, J., Deng, Z.L., Seidman, C.E., Seidman, J.G., Pu, W.T. and Wang, D.Z.* Cardiomyocyte-enriched protein CIP protects against pathophysiological stresses and regulates cardiac homeostasis. The Journal of clinical investigation. 2015, 125: 4122-4134. (IF: 19.456)

Huang, Z.P.#, Ding, Y.#*, Chen, J., Wu, G., Kataoka, M., Hu, Y., Yang, J.H., Liu, J., Drakos, S.G., Selzman, C.H., Kyselovic, J., Qu, L.H., dos Remedios C.G., Pu W.T. and Wang D.Z.* Long non-coding RNAs link extracellular matrix gene expression to ischemic cardiomyopathy. Cardiovascular Research. 2016, 112: 543-554.  (IF: 13.081)

Huang, Z.P.#, Chen, J.#, Seok, H.Y., Zhang, Z., Kataoka, M., Hu, X. and Wang, D.Z.* MicroRNA-22 Regulates Cardiac Hypertrophy and Remodeling in Response to Stress. Circulation Research, 2013, 112: 1234-1243. (IF: 23.213)

Huang, Z.P., Seok, H.Y., Zhou, B., Chen, J., Chen, J., Tao, Y., Pu, W.T., and Wang, D.Z.* CIP, a cardiac ISL1-interacting protein, represses cardiomyocyte hypertrophy. Circulation Research, 2012, 110: 818-830. (IF: 23.213)

Huang, Z.P., Chen, J.F., Regan, J.N., Maguire, C.T., Tang, R.H., Dong, X.R., Majesky, M.W., and Wang, D.Z.* Loss of MicroRNAs in Neural Crest Leads to Cardiovascular Syndromes Resembling Human Congenital Heart Defects. Arteriosclerosis, thrombosis, and vascular biology, 2010, 30: 2575-2586. (IF: 10.514)

其他主要工作成绩（比如获奖情况）：

    获广东省杰出青年医学人才、广东省“珠江人才计划”引进青年拔尖人才等人才项目/称号；曾获得美国国立卫生研究院的Ruth L. Kirschstein国家研究奖。主持国家自然科学基金委面上项目、广东省自然科学基金杰出青年项目、广东省国际科技合作领域项目等